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We hypothesized that HHcy induces arterial hypertension through the accumulation of ECM elements in between endothelial and arterial easy muscle cells, which results in subsequent endothelium-myocyte (E-M) uncoupling in response to MMP activation.This review short article is the initial to debate gypsogenin and its by-product from the medicinal che

Caudatin induced ubiquitin (Ub)-dependent glucocorticoid receptor (GR) degradation and blocked subsequent Indeed-involved protein (YAP) nuclear accumulation and goal gene transcription alerts in BCSCs. These final results show that the GR/YAP signaling pathway regulates BCSC formation and that caudatin could possibly be a possible chemopreventive a